The first medical educational programs at the Mayo Clinic were developed in 1915 with the assistance and direction of the University of Minnesota. The two institutions held close relationships in the early 20th century. William James Mayo was a Regent of the University of Minnesota and his brother Charles Horace Mayo was a professor of surgery at the University of Minnesota Medical School. In its early years the Mayo Clinic was operated as a for-profit hospital and could not affiliate with the University. This barrier led to the creation of the Mayo Foundation for Medical Education and Research in 1915.Along with the creation of the Mayo Foundation for Medical Education and Research, the Mayo Clinic donated $2 million to establish University of Minnesota Medical School graduate programs in Rochester at the Mayo Clinic the same year. During the same time period, the Mayo brothers created the Mayo Properties Association which converted the Mayo Clinic into a non-profit association practice. Mayo Properties Association later became the Mayo Foundation. These steps led to the University and Mayo Clinic to enter into an affiliation and teaching agreement. The curriculum during this period focused on the development of medical specialists during a time when the medical field was becoming further professionalized. Formal development of an independent medical doctorate program would not occur until 1970.
The Mayo Foundation appointed cardiologist Dr. Raymond Pruitt as the first dean of the Mayo Clinic School of Medicine in 1970, publicly announcing its creation the following year. It officially opened on September 5, 1972, with an inaugural class of 40 students, becoming the 110th medical school in the United States and the 2nd in Minnesota.
1: Science of Health Care Delivery I10: Circulation (Cardiology)
2: Basic Structure (Biochemistry, Genetics, and Histology)11: Oxygen (Pulmonology)
3: Ethics12: Hematology
4: Human Structure (Anatomy, Embryology, and Radiology)13: Musculoskeletal (Rheumatology, Orthopedics, and Physiatry)
5: Science of Health Care Delivery II14: Renal (Nephrology)
6: Normal Function (Pathology and Immunology)15: Urinary Tract (Urology)
7: Principles of Disease, Diagnosis, and Treatment (Microbiology and Pharmacology)16: Endocrinology
8: Neuroscience (Neurology)17: Gynecology (including Obstetrics)
9: Intro to Psychiatry18: Nutrition and Digestion (Gastroenterology and Hepatolog